![]() Remote controlled medical apparatus
专利摘要:
Abstract The invention relates to remote controlled blood cleaning of a patient. A dialysis unit treats the patient's blood in accordance with a prescribed therapy. The dialysis unit has a bi-directional wireless interface towards a 5 gateway unit, which is further connected to a remote host via at least one interconnecting network. Data representing at least one executed treatment of a patient is stored in the dialysis unit and is transmitted to the remote host via the gateway unit. The remote host transmits control data to the dialysis unit, the control data influencing the prescribed therapy 10 being, or to be, executed by the dialysis unit. (Fig. 1) 140 100 115 DbP Dr dh Dbp D 125 127 Dbp De 13 Dtrdh Dm.10W 112 130 %c 120 D %K Fig. 1 R c d210 Transmit control data from remote host + -220 Receive -control data in gateway unjit Transmit control data from gateway /230 unit over wireless interface Receive control data in dialysis unit Adapt prescribed therapy in 250 response to the control data Fig. 2 公开号:AU2013205933A1 申请号:U2013205933 申请日:2013-05-20 公开日:2013-06-06 发明作者:Johan Gagner;Sture Hobro;Jonas Klintberg;Fredrik Mattsson;Markus Nilsson 申请人:Gambro Lundia AB; IPC主号:A61M1-14
专利说明:
1 REMOTE CONTROLLED MEDICAL APPARATUS RELATED APPLICATION This application is a divisional application of Australian application no. 2007244000, the disclosure of which is incorporated herein by reference. 5 Most of the disclosure of that application is also included herein, however, reference may be made to the specification of application no. 2007244000 as accepted to gain further understanding of the invention claimed herein. THE BACKGROUND OF THE INVENTION AND PRIOR ART The present invention relates generally to a flexible and user-friendly 10 blood cleaning treatment, which can be performed in non-hospital environments, such as in the patient's home. More particularly the invention relates to a medical system according to the preamble of claim 1, a dialysis unit according to the preamble of claim 12 and a method according to the preamble of claim 13. The invention also relates to a 15 computer program according to claim 24 and a computer readable medium according to claim 25. The human body consists of approximately 60% water - a level which is important to maintain for survival. While it is unproblematic to provide the body with new water, disposal of surplus water is a major problem in renal 20 patients. One task of the normal kidney is to remove superfluous fluid from the blood, such as water, urea and other waste products. The resulting urine is transferred to the bladder and finally leaves the body during uri nation. The kidney's second task is to regulate for example the balance of electrolytes and acid and base. With malfunctioning kidneys, disorders 25 may develop in most major body organs, a syndrome called uremia. If uremia remains untreated, it will lead to death. Uremia is treated by kidney transplantation or some form of blood cleaning, either extracorporeal (e.g. in the form of hemodialysis, hemofiltration or hemodiafiltration), or intra corporal (e.g. in the form of peritoneal dialysis). 30 Irrespective of which type of blood cleaning treatment that is used, the treatment normally requires a substantial amount of time; say three times per week in four hours per session. Thus, for a good patient comfort and quality of life, it is key that the treatments can be completed in a manner being as straightforward and flexible as possible. To this aim, various 2 home dialysis solutions have been developed. Of course, a physician must supervise and analyze also these treatments. This can be accomplished by means of a smart card, which stores relevant therapy and treatment history data. The patient brings along his/her smart card when regularly 5 visiting the clinic, so that the physician can study the treatment history data, and if necessary update the therapy prescription, which is also stored on the card. However, the smart card has a limited storage capa city, and therefore this solution requires that the patient visit the clinic rather frequently. An online connection between a central location (e.g. a 10 hospital) and the home dialysis site may alleviate this problem. US 2003/0001743 describes a personal and/or institutional health and wellness communications system, wherein a bi-directional communication is established over a network between a personal medical device and a central monitoring station. The medical device, which may be adapted to 15 perform kidney dialysis, preferably communicates wirelessly with a local network node (e.g. according to the Bluetooth standard). US 6,406,426 discloses a medical monitoring and alert system, which can be used with therapeutic devices, such as hemodialysis machines. Here, a connection is set up between a therapeutic device and a central 20 monitoring system. This connection, which may include hardwired as well as wireless bi-directional links, enables patient information follow-ups, sta tistics, software updates and remote testing of the therapeutic device. Naturally, the above-mentioned online connections between the remote host and the dialysis machine constitute improvements in relation to the 25 smart card solution, for instance with regard to adjustments and testing of the dialysis machine as such. However still, a qualified caregiver must manually personalize the machine to meet the patient specific needs whenever the prescribed therapy is to be modified, and/or be adapted to the patient's current condition. 30 SUMMARY OF THE INVENTION In a first broad aspect the invention provides a medical system for cleaning the blood of a patient, the system comprising: a dialysis unit adapted to treat the patient's blood in accordance with a prescribed therapy, the dialysis unit having a wireless interface for bi-directional 35 exchange of data, and a gateway unit adapted to communicate with the 3 dialysis unit over the wireless interface, the gateway unit having an in terface adapted to be connected to a remote host via at least one interconnecting network, and the gateway unit being adapted to provide a bi-directional exchange of data between the remote host and the dialysis 5 unit, wherein the dialysis unit is adapted to: store data representing at least one executed treatment of a patient; transmit at least a fraction of the stored data to the remote host via the gateway unit; receive control data from the remote host via the gateway unit; and influence the prescribed therapy in response to control data. Consequently, the dialysis 10 process may be adapted in real time depending on how the patient responds to the treatment. An important advantage attained by this design is that any therapy updates and modifications can be effected smoothly and efficiently. According to one preferred embodiment of this aspect of the invention, the 15 control data defines at least one parameter of a prescribed therapy of a future treatment of the patient. Moreover, the dialysis unit is adapted to perform the future treatment in accordance with a prescribed therapy being adjusted with respect to the at least one parameter. Thus, based on the result of one treatment, a following therapy may be prescribed, either 20 as a variation of the previous therapy, or as an entirely new therapy. According to another preferred embodiment of this aspect of the invention, the dialysis unit is adapted to transmit at least one effect parameter to the remote host via the gateway unit. The effect parameter reflects a result of a treatment performed by the dialysis unit. Naturally, the effect parameter 25 may provide information that aids the physician in his/her diagnosis work. According to still another preferred embodiment of this aspect of the invention, the system includes a blood pressure monitor adapted to register at least one blood pressure related parameter in respect of the patient. The blood pressure monitor has a wireless interface towards the 30 gateway unit, so that the monitor can transmit said at least one parameter to the gateway unit. The gateway unit, in turn, may be adapted to transmit these records further to the remote host. Thereby, the remote host can gain valuable information about the patient's current condition, as well as how his/her health status develops during the treatment. 35 According to another preferred embodiment of this aspect of the invention, the dialysis unit is adapted to transmit at least one machine parameter to 4 the remote host via the gateway unit. This at least parameter reflects a status, or a setting of, at least one characteristic of the dialysis unit. Thus, the remote host may log for example relevant pressures, fluid flows, temperatures, and settings of valves during the treatment. This aids the 5 diagnosis, as well as facilitates the hardware maintenance and service. According to yet another preferred embodiment of this aspect of the inven tion, the system includes a scale unit adapted to register a weight parameter in respect of the patient (typically the patient's body weight). Analogous to the above-mentioned blood pressure monitor, the scale unit 10 has a wireless interface towards the gateway unit, and the scale unit is adapted to transmit the weight parameter to the gateway unit, which in turn, is adapted to transmit this data to the remote host. Consequently, the remote host can be informed about the patient's current weight, which is a vital factor for many diagnosis and therapy decisions. Moreover, if the 15 scale unit is configured to register the weight parameter during the dialysis treatment, conclusions can be drawn regarding the water level balance based on how the weight fluctuates as the treatment progresses. According to a further preferred embodiment of this aspect of the inven tion, the dialysis unit includes a memory module adapted to store data 20 representing at least one executed treatment of the patient. The dialysis unit may also be adapted to transmit at least a fraction of the stored data to the remote host via the gateway unit. Hence, the remote host can be informed of the outcome of previous therapies. Naturally, this is valuable information to the physician when prescribing new therapies. 25 According to yet another preferred embodiment of this aspect of the inven tion, the dialysis unit includes at least one software module adapted to control at least one function of the dialysis unit. Furthermore, the dialysis unit is adapted to receive software updating data from the remote host via the gateway unit. In response to the software updating data, the dialysis 30 unit is adapted to modify at least one of its software modules. Thus, the modus operandi of the dialysis unit can be modified from, or be determined by, the remote host. According to another preferred embodiment of this aspect of the invention, the system includes a first data input unit (e.g. a personal digital assistant 35 PDA), which is adapted to register manually entered information. The first data input unit has a wireless interface towards the gateway unit, and the 5 data input unit is also adapted to transmit the manually entered information to the remote host via the gateway unit. Hence, the patient may enter subjective information, such as how he/she experienced the treatment and/or his/her current physical condition. Of course, this kind of 5 information may be valuable for the physician when prescribing future therapies. According to still another preferred embodiment of this aspect of the invention, the system includes a second data input unit (e.g. a bar code reader), which is adapted to automatically register machine readable 10 information. The second data input unit is also adapted to forward the machine readable information to the remote host via the gateway unit. This transfer of data may be effected via the above-mentioned first data input unit, or directly to the gateway unit. In a second broad aspect the invention provides a dialysis unit adapted to 15 clean the blood of a patient in accordance with a prescribed therapy, the dialysis unit having a first wireless interface for bi-directional exchange of data, and the dialysis unit being adapted to communicate with a remote host via a gateway unit having a second wireless interface matched to the first wireless interface, gateway unit being further connected to the remote 20 host via at least one interconnecting network, wherein the dialysis unit is adapted to store data representing at least one executed treatment of a patient, transmit at least a fraction of the stored data to the remote host via the gateway unit, receive control data from the remote host via the gateway unit; and influence the prescribed therapy in response to control 25 data received from the remote host via the gateway unit. Thus, any therapy updates and modifications of the treatment performed by the dialysis unit can be effected smoothly and efficiently. In a third broad aspect the invention provides a method for controlling a medical system adapted to clean the blood of a patient, the method 30 comprising: exchanging bi-directional data wirelessly between a gateway unit and a dialysis unit, the dialysis unit being adapted to treat the patient's blood in accordance with a prescribed therapy, and the gateway unit being further connected to a remote host via at least one interconnec ting network; exchanging bi-directional data between the remote host and 35 the gateway unit; storing data representing at least one executed treatment of a patient in the dialysis unit; transmitting at least a fraction of 6 the stored data to the remote host via the gateway unit; receiving in the gateway unit control data transmitted from the remote host; transmitting the control data from the gateway unit to the dialysis unit over the wireless interface; receiving the control data in the dialysis unit, and in response to 5 the control data; modifying at least one parameter of the prescribed therapy. The advantages of this method, as well as the preferred embodiments thereof, are apparent from the discussion hereinabove with reference to the proposed medical system. In a fourth broad aspect the invention provides a computer program 10 directly loadable into the internal memory of a computer, comprising software for controlling the method of the third broad aspect when said program is run on a computer. In a fifth broad aspect the invention provides a computer readable medium, having a program recorded thereon, where the program is to 15 make a computer control the method of the third broad aspect. In another broad aspect the invention may provide a medical system for cleaning the blood of a patient, the system comprising: a dialysis unit adapted to treat the patient's blood in accordance with a prescribed therapy, the dialysis unit having a wireless interface for bi-directional 20 exchange of data, and a gateway unit adapted to communicate with the dialysis unit over the wireless interface, the gateway unit having an interface adapted to be connected to a remote host via at least one interconnecting network, and the gateway unit being adapted to provide a bi-directional exchange of data between the remote host and the dialysis 25 unit, wherein the dialysis unit is adapted to: transmit therapy result and/or patient status data to the remote host via the gateway unit during the treatment; and influence the prescribed therapy in response to control data received from the remote host via the gateway unit, the control data being received during an ongoing treatment of the patient, and modify at least 30 one parameter of the prescribed therapy in respect of the ongoing treatment before completing this treatment. In another broad aspect the invention may provide a dialysis unit adapted to clean the blood of a patient in accordance with a prescribed therapy, the dialysis unit having a first wireless interface for bi-directional 35 exchange of data, and the dialysis unit being adapted to communicate with a remote host via a gateway unit having a second wireless interface 7 matched to the first wireless interface, gateway unit being further connected to the remote host via at least one interconnecting network, wherein the dialysis unit is adapted to transmit therapy result and/or patient status data to the remote host via the gateway unit during the 5 treatment and influence the prescribed therapy in response to control data received from the remote host via the gateway unit, the control data being received during an ongoing treatment of the patient, and the dialysis unit is adapted to modify at least one parameter of the prescribed therapy in respect of the ongoing treatment before completing this treatment. 10 In another broad aspect the invention may provide a method for controlling a medical system adapted to clean the blood of a patient, the method comprising: exchanging bi-directional data wirelessly between a gateway unit and a dialysis unit, the dialysis unit being adapted to treat the patient's blood in accordance with a prescribed therapy, and the gateway 15 unit being further connected to a remote host via at least one interconnecting network, exchanging bi-directional data between the remote host and the gateway unit, receiving in the gateway unit therapy result and/or patient status data transmitted from the dialysis unit over the wireless interface, transmitting the therapy result and/or patient status 20 data from the gateway unit to the remote host during the treatment, receiving in the gateway unit control data transmitted from the remote host, transmitting the control data from the gateway unit to the dialysis unit over the wireless interface, receiving the control data in the dialysis unit during an ongoing treatment of the patient, and in response to the 25 control data, modifying at least one parameter of the prescribed therapy in respect of the ongoing treatment before completing this treatment. Another broad aspect may provide a computer program directly loadable into the internal memory of a computer, comprising software for controlling the steps of any of the above-mentioned methods. Another broad aspect 30 may provide a computer readable medium, having a program recorded thereon, where the program is to make a computer control the steps of any of the above-mentioned methods. Further advantages, advantageous features and applications of the present invention will be apparent from the following description and the 35 dependent claims. 8 BRIEF DESCRIPTION OF THE DRAWINGS The present invention is now to be explained more closely by means of preferred embodiments, which are disclosed as examples, and with reference to the attached drawings. 5 Figure 1 shows a block diagram over a medical system according to a one embodiment of the invention, and Figure 2 shows a flow diagram which illustrates the general method according to the invention. DESCRIPTION OF PREFERRED EMBODIMENTS OF THE INVENTION 10 Figure 1 shows one embodiment of a proposed medical system 100 for cleaning the blood of a patient P under supervision of a central resource. The system 100 includes a dialysis unit 110, a gateway unit 120 and a remote host 140. The dialysis unit 110 is adapted to treat the patient's P blood in 15 accordance with a prescribed therapy by means of an extra- or an intracorporal treatment process. In any case, the dialysis unit 110 has a wireless interface 110W for bi-directional exchange of data, i.e. for receiving a first type of data Dctri and Ds, and for transmitting a second type of data Dr and Dh. The wireless interface 110W is preferably adapted 20 to the Bluetooth standard and/or Zigbee standard. Alternatively, the wireless interface 110W implements an infrared interface or it is based on another type of short-range wireless technology. The gateway unit 120 has a matching wireless interface 120W, i.e. an interface that is adapted to communicate with the dialysis unit 110 over 25 the interface 110W. Moreover, the gateway unit 120 has an interface 125, which is adapted to be connected to the remote host 140 via at least one interconnecting network 130. Depending on the interface format of a relevant access node to the network(s) 130, the interface 125 may be a wireless and/or a wire-bound interface. For example, if the access node is 30 an Internet node, a PSTN node or a LAN node, the interface 125 is preferably wire-bound; whereas if the access node is a PLMN node or a WLAN node, the interface 125 is preferably wireless (PSTN = Public Switched Telephone Network; PLMN = Public Land Mobile Network (e.g. GSM, GPRS or 3G/UMTS); WLAN = Wireless Local-Area Network). Thus, 9 by means of the interfaces 125 and 120W respectively, the gateway unit 120 is adapted to provide a bi-directional exchange of data between the remote host 140 and the dialysis unit 110. Specifically, the gateway unit 120 is adapted to receive therapy result Dr; Dh and patient status data Dbp 5 and Dw over the wireless interface 120W. The gateway unit 120 is also adapted to receive control data Detri from the remote host 140 via the interface 125 and to forward the control data Dtri over the wireless interface 120W to the dialysis unit 110. Furthermore, the dialysis unit 110 is adapted to influence the prescribed therapy in response to the received 10 control data Detri The proposed gateway unit 120 is advantageous in that it standardizes the interface towards the dialysis unit, i.e. the gateway unit 120 renders the dialysis unit 110 independent from the format of any interconnecting networks 130. More importantly, however, the gateway unit 120 can 15 ensure that the connection to the remote host 140 is protected against spoofing and eavesdropping, without requiring any security measures in the dialysis unit 110. Instead, the necessary encryption and authentication can be negotiated between the remote host 140 and the gateway unit 120. Of course, if the wireless interface 11OW-120W is based on Bluetooth or 20 Zigbee technology, the encryption and authentication available under these standards are preferably used to protect also the link between the gateway unit 120 and the dialysis unit 110. According to one preferred embodiment of the invention, the dialysis unit 110 is adapted to receive the control data Detri during an ongoing 25 treatment of the patient P, and in response to the data Dtri modify at least one parameter of the prescribed therapy in respect of the ongoing treatment before completing this treatment. The control data Dtri may also define at least one parameter of a prescribed therapy of a future treatment of the patient P (i.e. a treatment 30 that has not yet been initiated). To this aim, the dialysis unit 110 includes a storage module (not shown), which is adapted to store the at least one parameter at least until said future treatment is to be completed. Of course, the dialysis unit 110 is then configured to perform the future treatment in accordance with a prescribed therapy that has been adjusted 35 with respect to the at least one parameter. Dialysis liquid volumes, treatments times and UF (Ultra Filtration) values constitute examples of 10 such parameters. Depending on the type, number and extent of parameters included in the control data Detr, this data may define up to an entire prescribed therapy of a future treatment of the patient P. 5 Since the wireless interface 110W is bi-directional, the dialysis unit 110 may also transmit uplink information to the gateway unit 120. For example, according to one preferred embodiment of the invention, the dialysis unit 110 is adapted to transmit at least one effect parameter Dr to the gateway unit 120. The at least one effect parameter Dr may include data 10 representing a glucose concentration in the patient's P blood and/or a body water level. The gateway unit 120, in turn, is adapted to forward the at least one effect parameter Dr to the remote host 140. The effect parameter(s) Dr reflect/s a result of a treatment performed by the dialysis unit 110. Hence, based on 15 this/these parameter/s conclusions can be drawn at the remote host 140 whether or not the treatment was successful. According to one preferred embodiment of the invention, the system 100 includes a blood pressure monitor 115, which is adapted to register at least one blood pressure related parameter in respect of the patient P 20 (typically the diastolic pressure, the systolic pressure, the pulse and/or the medium arterial pressure, MAP). The monitor 115 has a wireless interface 115W towards the gateway unit 120, such that at least one of the at least one blood pressure related parameter Dbp can be transmitted to the remote host 140 via the gateway unit 120. 25 Preferably, the dialysis unit 110 is adapted to transmit at least one machine parameter Dm to the remote host 140 via the gateway unit 120. The at least one machine parameter Dm reflects a status for at least one characteristic of the dialysis unit 110, such as one or more pressure levels, various fluid flow rates, and/or liquid temperatures at different 30 instances during the treatment. Alternatively, or as a complement thereto, the at least one machine parameter Dm may reflect a settings of various components, e.g. valves, in the dialysis unit 110. Thus, the remote host 140 may log the behavior of the dialysis unit 110. Consequently, the physician is aided in his/her diagnosis work. The hardware maintenance 35 and service are also facilitated. 11 Preferably, the system 100 includes a scale unit 117, which is adapted to register a weight parameter Dw in respect of the patient P, such as the entire body weight. The scale unit 117 has a wireless interface 117W to wards the gateway unit 120. Thus, the scale unit 117 can transmit the 5 weight parameter Dw to the remote host 140 via the gateway unit 120. According to one preferred embodiment of the invention, the dialysis unit 110 may include, or be associated with, a memory module 111, which is adapted to store data Dh representing at least one executed treatment of the patient P (i.e. completed treatments as well as any treatments having 10 been aborted before being completed). Furthermore, the dialysis unit 110 is adapted to transmit at least a fraction dh of the stored data Dh to the remote host 140 via the gateway unit 120. Hence, the remote host 140 can be informed of some or all characteristics of one or more earlier treatments. 15 According to one preferred embodiment of the invention, the system includes a first data input unit 118 (e.g. a PDA, a laptop or a smart phone), which is adapted to register manually entered information Dp. This information Dp relates to subjective data, such as how the patient experienced the treatment, or the patient's current physical condition. The 20 first data input unit 118 has a wireless interface towards the gateway unit 120, and the unit 118 is adapted to transmit the manually entered information Dp to the remote host 140 via the gateway unit 120. Thereby, a physician at the remote host 140 can gain valuable information regarding the treatment, which may be helpful when prescribing future treatments. 25 Additionally, the first data input unit 118 may be adapted to register event data, i.e. actions performed by the patient such as alarm acknowledgements or a premature ending of a treatment, and forward this data to the remote host 140 via the gateway unit 120. It is also desirable if the system includes a second data input unit 119 30 (e.g. a bar code reader or a portable OCR scanner (OCR = Optical Character Recognition), which is adapted to automatically register machine readable information. Furthermore, the unit 119 is adapted to forward the machine-readable information to the remote host 140 via the gateway unit 120. This information transfer may either be effected via the 35 first data input unit 118, as illustrated in Figure 1, or over the gateway unit 120 directly (for instance over the wireless interface 120W). By means of 12 the second data input unit 119, the user may enter data pertaining to the dialysis fluid used, and thus provide the remote host with vital treatment information. Preferably, the dialysis unit 110 includes, or is associated with, a 5 computer readable medium 112, e.g. a memory module, which stores software for controlling the above-described functionality. The software, in turn, contains at least one software module that is adapted to control at least one function of the dialysis unit 110. Moreover, the dialysis unit 110 is adapted to receive software-updating data Ds, from the remote host 140 10 via the gateway unit 120. In response to the software updating data Ds,, the dialysis unit 110 is adapted to modify at least one of the at least one software modules. Thus, the modus operandi of the dialysis unit 110 can be altered/updated from the remote host 140. In order to sum up, the general method according to the invention will be 15 described below with reference to the flow diagram in figure 2. A first step 210 transmits control data Detri from the remote host 140 to the gateway unit 120 (i.e. over the at least one interconnecting network 130). A step 220 then receives the control data in the gateway unit 120. Subsequently, a step 230 transmits the control data Detri from the gateway 20 unit 120 to the dialysis unit 110 over the wireless interface 120W-110W. Thereafter, a step 240 receives the control data Detri in the dialysis unit 110. Finally, the prescribed therapy to be performed by the dialysis unit 110 is adapted in response to the received control data Detri. According to a preferred embodiment of the invention, the method also 25 involves transmitting an acceptance message from the dialysis unit 110 over the wireless interface to the gateway unit (e.g. between steps 240 and 250). The acceptance message acknowledges reception of the control data Detri in the dialysis unit 110. It is further preferable if the gateway unit 120 is adapted to retransmit the control data Detri to the dialysis unit 110 30 until such an acceptance message has been received. Moreover, upon re ceipt of the acceptance message, the dialysis unit 110 is preferably adapted to forward the acceptance message (or any equivalent message) to the remote host 140. Thereby, the remote host 140 can be informed of the fact that the prescribed therapy and/or the modus operandi the dialysis 35 unit 110 will be updated as desired. 13 All of the process steps, as well as any sub-sequence of steps, described with reference to the figure 2 above may be controlled by means of a programmed computer apparatus. Moreover, although the embodiments of the invention described above with reference to the drawings comprise 5 computer apparatus and processes performed in computer apparatus, the invention thus also extends to computer programs, particularly computer programs on or in a carrier, adapted for putting the invention into practice. The program may be in the form of source code; object code, a code intermediate source and object code such as in partially compiled form, or 10 in any other form suitable for use in the implementation of the process according to the invention. The carrier may be any entity or device capable of carrying the program. For example, the carrier may comprise a storage medium, such as a Flash memory, a ROM (Read Only Memory), for example a CD (Compact Disc) or a semiconductor ROM, an EPROM 15 (Erasable Programmable Read-Only Memory), an EEPROM (Electrically Erasable Programmable Read-Only Memory), or a magnetic recording medium, for example a floppy disc or hard disc. Further, the carrier may be a transmissible carrier such as an electrical or optical signal which may be conveyed via electrical or optical cable or by radio or by other means. 20 When the program is embodied in a signal which may be conveyed directly by a cable or other device or means, the carrier may be constituted by such cable or device or means. Alternatively, the carrier may be an integrated circuit in which the program is embedded, the integrated circuit being adapted for performing, or for use in the performance of, the 25 relevant processes. The term "comprises/comprising" when used in this specification is taken to specify the presence of stated features, integers, steps or components. However, the term does not preclude the presence or addition of one or more additional features, integers, steps or components or groups thereof. 30 The reference to any prior art in this specification is not, and should not be taken as, an acknowledgement or any suggestion that the referenced prior art forms part of the common general knowledge in Australia. The invention is not restricted to the described embodiments in the figures, but may be varied freely within the scope of the claims. 35
权利要求:
Claims (30) [1] 1. A medical system for cleaning the blood of a patient, the system comprising: 5 a dialysis unit adapted to treat the patient's blood in accordance with a prescribed therapy, the dialysis unit having a wireless interface for bi-directional exchange of data, and a gateway unit adapted to communicate with the dialysis unit over the wireless interface, the gateway unit having an interface adapted to be 10 connected to a remote host via at least one interconnecting network, and the gateway unit being adapted to provide a bi-directional exchange of data between the remote host and the dialysis unit, wherein the dialysis unit is adapted to: store data representing at least one executed treatment of a patient; 15 transmit at least a fraction of the stored data to the remote host via the gateway unit; receive control data from the remote host via the gateway unit; and influence the prescribed therapy in response to control data. [2] 2. The system according to claim 1, wherein the control data defines at 20 least one parameter of a prescribed therapy of a future treatment of the patient, and the dialysis unit is adapted to perform the future treatment in accordance with a prescribed therapy being adjusted with respect to the at least one parameter. [3] 3. The system according to claim 2, wherein the control data defines 25 an entire prescribed therapy of a future treatment of the patient. [4] 4. The system according to any one of the preceding claims, wherein the dialysis unit is adapted to transmit at least one effect parameter to the remote host via the gateway unit, the at least one effect parameter reflec ting a result of a treatment performed by the dialysis unit. 30 [5] 5. The system according to any one of the preceding claims, wherein the system comprises a blood pressure monitor adapted to register at least one blood pressure related parameter in respect of the patient, the blood pressure monitor having a wireless interface towards the gateway unit, and the blood pressure monitor being adapted to transmit at least one 15 of the at least one blood pressure related parameter to the remote host via the gateway unit. [6] 6. The system according to any one of the preceding claims, wherein the dialysis unit is adapted to transmit at least one machine parameter to 5 the remote host via the gateway unit, the at least one machine parameter reflecting a status or a setting of at least one characteristic of the dialysis unit. [7] 7. The system according to any one of the preceding claims, wherein the system comprises a scale unit adapted to register a weight parameter 10 in respect of the patient, the scale unit having a wireless interface towards the gateway unit, and the scale unit being adapted to transmit the weight parameter to the remote host via the gateway unit. [8] 8. The system according to any one of the preceding claims, wherein the dialysis unit comprises a memory module adapted to store the data 15 representing at least one executed treatment of the patient. [9] 9. The system according to any one of the preceding claims, wherein the dialysis unit comprises at least one software module adapted to control at least one function of the dialysis unit, and the dialysis unit is adapted to: 20 receive software updating data from the remote host via the gateway unit, and modify at least one of the at least one software module in response to the software updating data. [10] 10. The system according to any one of the preceding claims, 25 comprising a first data input unit adapted to register manually entered information, the first data input unit having a wireless interface towards the gateway unit, and the data input unit being adapted to transmit the manually entered information to the remote host via the gateway unit. [11] 11. The system according to any one of the preceding claims, 30 comprising a second data input unit adapted to: automatically register machine readable information, and forward the machine readable information to the remote host via the 16 gateway unit. [12] 12. A dialysis unit adapted to clean the blood of a patient in accordance with a prescribed therapy, the dialysis unit having a first wireless interface for bi-directional exchange of data, and the dialysis unit being adapted to 5 communicate with a remote host via a gateway unit having a second wireless interface matched to the first wireless interface, gateway unit being further connected to the remote host via at least one interconnecting network, wherein the dialysis unit is adapted to store data representing at least one executed treatment of a patient, transmit at least a fraction of 10 the stored data to the remote host via the gateway unit, receive control data from the remote host via the gateway unit; and influence the prescribed therapy in response to control data received from the remote host via the gateway unit. [13] 13. A method for controlling a medical system adapted to clean the 15 blood of a patient, the method comprising: exchanging bi-directional data wirelessly between a gateway unit and a dialysis unit, the dialysis unit being adapted to treat the patient's blood in accordance with a prescribed therapy, and the gateway unit being further connected to a remote host via at least one interconnecting 20 network; exchanging bi-directional data between the remote host and the gateway unit; storing data representing at least one executed treatment of a patient in the dialysis unit; 25 transmitting at least a fraction of the stored data to the remote host via the gateway unit; receiving in the gateway unit control data transmitted from the remote host; transmitting the control data from the gateway unit to the dialysis 30 unit over the wireless interface; receiving the control data in the dialysis unit, and in response to the control data; modifying at least one parameter of the prescribed therapy. [14] 14. The method according to claim 13, wherein the control data defines 35 at least one parameter of a prescribed therapy of a future treatment of the 17 patient, and the method comprises performing the future treatment in accordance with a prescribed therapy being adjusted with respect to the at least one parameter. [15] 15. The method according to claim 14, wherein the control data defines 5 an entire prescribed therapy of a future treatment of the patient. [16] 16. The method according to any one of the claims 13 to 15, comprising transmitting at least one effect parameter from the dialysis unit to the remote host via the gateway unit, the effect parameter reflecting a result of a treatment performed by the dialysis unit. 10 [17] 17. The method according to any one of the claims 13 to 16, comprising: receiving at least one blood pressure related parameter in respect of the patient in the gateway unit, and transmitting the at least one blood pressure related parameter to the 15 remote host from the gateway unit. [18] 18. The method according to any one of the claims 13 to 17, comprising: receiving at least one machine parameter in the gateway unit, the at least one machine parameter reflecting a status or a setting for at least 20 one characteristic of the dialysis unit, and transmitting the at least one machine parameter to the remote host from the gateway unit. [19] 19. The method according to any one of the claims 13 to 18, comprising: 25 receiving a weight parameter in respect of the patient in the gate way unit, and transmitting the weight parameter to the remote host from the gateway unit. [20] 20. The method according to any one of the claims 13 to 19, 30 comprising: receiving software updating data from the remote host in the gateway unit, 18 transmitting the software updating data from the gateway unit to the dialysis unit, receiving the software updating data in the dialysis unit, and modifying at least one software module therein in response to the 5 software updating data, the at least one software module being adapted to control at least one function of the dialysis unit. [21] 21. The method according to any one of the claims 13 to 20, comprising: receiving manually entered information in the gateway unit, and transmitting the manually entered information from the gateway unit 10 to the remote host from the gateway unit. [22] 22. The method according to any one of the claims 13 to 21, comprising: receiving automatically registered machine readable information in the gateway unit, and transmitting the machine readable information from the gateway unit 15 to the remote host from the gateway unit. [23] 23. The method according to any one of the claims 13 to 22, comprising: transmitting an acceptance message from the dialysis unit over the wireless interface to the gateway unit, the acceptance message being adapted to acknowledge reception of the control data in the dialysis unit, 20 and forwarding the acceptance message from the gateway unit to the remote host. [24] 24. A computer program directly loadable into the internal memory of a computer, comprising software for controlling the steps of any of the 25 claims 13 to 23 when said program is run on the computer. [25] 25. A computer readable medium, having a program recorded thereon, where the program is to make a computer control the steps of any of the claims 13 to 23. 30 [26] 26. A medical system according to claim 1 substantially as herein described or exemplified. [27] 27. A dialysis unit according to claim 12 substantially as herein 19 described or exemplified. [28] 28. A method according to claim 13 substantially as herein described or exemplified. 5 [29] 29. A computer program according to claim 24 substantially as herein described or exemplified. [30] 30. A computer readable medium according to claim 25 substantially as 10 herein described or exemplified.
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同族专利:
公开号 | 公开日 EP2012848B1|2019-07-24| CA2647361A1|2007-11-08| EP2012848A1|2009-01-14| AU2013205933B2|2015-04-02| WO2007126360A8|2008-10-09| AU2007244000A1|2007-11-08| WO2007126360A1|2007-11-08| AU2007244000B2|2013-03-14| US20090306573A1|2009-12-10| ES2744210T3|2020-02-24| EP2012848A4|2013-12-25| CA2647361C|2016-03-08|
引用文献:
公开号 | 申请日 | 公开日 | 申请人 | 专利标题 US4370983A|1971-01-20|1983-02-01|Lichtenstein Eric Stefan|Computer-control medical care system| US5157603A|1986-11-06|1992-10-20|Storz Instrument Company|Control system for ophthalmic surgical instruments| US5151082A|1988-08-05|1992-09-29|Heathdyne, Inc.|Apparatus and method for kidney dialysis using plasma in lieu of blood| JPH02228939A|1989-03-03|1990-09-11|Fukuda Denshi Co Ltd|System for monitoring patient by use of lan| US5276611A|1989-05-25|1994-01-04|Andrea Ghiraldi|Management of parameters relating to a dialysis treatment| WO1992004806A1|1990-08-31|1992-03-19|The General Hospital Corporation|A network for portable patient monitoring devices| IT1255260B|1991-07-16|1995-10-20|Hospal Dasco Spa|METHOD OF SURVEILLANCE OF A THERAPY IN A DIALYTIC TREATMENT.| US5544649A|1992-03-25|1996-08-13|Cardiomedix, Inc.|Ambulatory patient health monitoring techniques utilizing interactive visual communication| US5357427A|1993-03-15|1994-10-18|Digital Equipment Corporation|Remote monitoring of high-risk patients using artificial intelligence| US5788851A|1995-02-13|1998-08-04|Aksys, Ltd.|User interface and method for control of medical instruments, such as dialysis machines| US5653887A|1995-06-07|1997-08-05|Cobe Laboratories, Inc.|Apheresis blood processing method using pictorial displays| US6689091B2|1996-08-02|2004-02-10|Tuan Bui|Medical apparatus with remote control| US5885245A|1996-08-02|1999-03-23|Sabratek Corporation|Medical apparatus with remote virtual input device| US5895371A|1996-08-27|1999-04-20|Sabratek Corporation|Medical treatment apparatus and method| US6852090B2|1997-02-14|2005-02-08|Nxstage Medical, Inc.|Fluid processing systems and methods using extracorporeal fluid flow panels oriented within a cartridge| US6673314B1|1997-02-14|2004-01-06|Nxstage Medical, Inc.|Interactive systems and methods for supporting hemofiltration therapies| US7771379B2|2001-05-24|2010-08-10|Nxstage Medical, Inc.|Functional isolation of upgradeable components to reduce risk in medical treatment devices| US6039251A|1998-04-16|2000-03-21|Holowko; Paul L.|Method and system for secure control of a medical device| US6759956B2|1998-10-23|2004-07-06|Royal Thoughts, L.L.C.|Bi-directional wireless detection system| US7088233B2|1998-10-23|2006-08-08|Royal Thoughts, Llc|Personal medical device communication system and method| US6804656B1|1999-06-23|2004-10-12|Visicu, Inc.|System and method for providing continuous, expert network critical care services from a remote location| US6264614B1|1999-08-31|2001-07-24|Data Critical Corporation|System and method for generating and transferring medical data| BR0014096B1|1999-09-21|2009-08-11||remote unit for monitoring the vital signs of a plurality of people from a central point.| US6406426B1|1999-11-03|2002-06-18|Criticare Systems|Medical monitoring and alert system for use with therapeutic devices| US20010027384A1|2000-03-01|2001-10-04|Schulze Arthur E.|Wireless internet bio-telemetry monitoring system and method| FR2806561B1|2000-03-16|2002-08-09|France Telecom|HOME TELE ASSISTANCE SYSTEM| DE10049393A1|2000-10-05|2002-04-25|Braun Melsungen Ag|Extracorporeal blood treatment system| US6585675B1|2000-11-02|2003-07-01|Chf Solutions, Inc.|Method and apparatus for blood withdrawal and infusion using a pressure controller| JP2005500869A|2001-03-28|2005-01-13|テレバイタル・インコーポレイテッド|System and method for real-time monitoring, judgment, analysis, retrieval and storage of physiological data over a wide area network| US20030134095A1|2002-01-16|2003-07-17|Bottari Frank J|Method of applying an edge electrode pattern to a touch screen| US20050055244A1|2003-07-18|2005-03-10|Janet Mullan|Wireless medical communication system and method| US8489427B2|2002-01-29|2013-07-16|Baxter International Inc.|Wireless medical data communication system and method| US7698156B2|2002-01-29|2010-04-13|Baxter International Inc.|System and method for identifying data streams associated with medical equipment| US7033539B2|2002-05-24|2006-04-25|Baxter International Inc.|Graphical user interface for automated dialysis system| US7027871B2|2002-10-31|2006-04-11|Medtronic, Inc.|Aggregation of data from external data sources within an implantable medical device| DE102004011264B4|2003-03-11|2014-03-27|B. Braun Medizintechnologie Gmbh|dialysis Center| US20040193325A1|2003-03-25|2004-09-30|David Bonderud|Method and apparatus to prevent medication error in a networked infusion system| WO2005044088A2|2003-11-03|2005-05-19|Children's Medical Center Corporation|Continuous analyte monitor and method of using same| DE102004012447A1|2004-03-13|2005-10-06|B. Braun Medizintechnologie Gmbh|Medical treatment system| DE102005025516A1|2005-06-03|2006-12-07|Fresenius Medical Care Deutschland Gmbh|Medical treatment system with a device for providing patient-related data| US20060277072A1|2005-06-06|2006-12-07|Cindy Bell|System for creating a medical chart| WO2007053683A2|2005-11-01|2007-05-10|Fresenius Medical Care Holdings, Inc.|Digital data entry methods and devices| US20100137693A1|2005-11-01|2010-06-03|Fresenius Medical Care Holdings, Inc.|Methods and systems for patient care| US20070158268A1|2006-01-06|2007-07-12|Decomo Peter|Dual purpose acute and home treatment dialysis machine| US7749164B2|2006-06-28|2010-07-06|The General Electric Company|System and method for the processing of alarm and communication information in centralized patient monitoring| EP2084633A2|2006-11-21|2009-08-05|Baxter International Inc.|System and method for remote monitoring and/or management of infusion therapies| US8543420B2|2007-09-19|2013-09-24|Fresenius Medical Care Holdings, Inc.|Patient-specific content delivery methods and systems| US8323503B2|2008-06-11|2012-12-04|Fresenius Medical Care Holdings, Inc.|User interface processing device| US20100274098A1|2008-10-23|2010-10-28|Edwards Lifesciences Corporation|Patient Monitoring System| US9370324B2|2008-11-05|2016-06-21|Fresenius Medical Care Holdings, Inc.|Hemodialysis patient data acquisition, management and analysis system|AU2003230862A1|2002-04-11|2003-10-27|Deka Products Limited Partnership|System and method for delivering a target volume of fluid| US8029454B2|2003-11-05|2011-10-04|Baxter International Inc.|High convection home hemodialysis/hemofiltration and sorbent system| US10537671B2|2006-04-14|2020-01-21|Deka Products Limited Partnership|Automated control mechanisms in a hemodialysis apparatus| CA3099207A1|2006-04-14|2007-10-25|Deka Products Limited Partnership|Systems, devices and methods for fluid pumping, heat exchange, thermal sensing, and conductivity sensing| US8366316B2|2006-04-14|2013-02-05|Deka Products Limited Partnership|Sensor apparatus systems, devices and methods| KR102160985B1|2007-02-27|2020-09-29|데카 프로덕츠 리미티드 파트너쉽|Hemodialysis system| US9028691B2|2007-02-27|2015-05-12|Deka Products Limited Partnership|Blood circuit assembly for a hemodialysis system| US8409441B2|2007-02-27|2013-04-02|Deka Products Limited Partnership|Blood treatment systems and methods| US8042563B2|2007-02-27|2011-10-25|Deka Products Limited Partnership|Cassette system integrated apparatus| US8357298B2|2007-02-27|2013-01-22|Deka Products Limited Partnership|Hemodialysis systems and methods| US8562834B2|2007-02-27|2013-10-22|Deka Products Limited Partnership|Modular assembly for a portable hemodialysis system| US8491184B2|2007-02-27|2013-07-23|Deka Products Limited Partnership|Sensor apparatus systems, devices and methods| US20090107335A1|2007-02-27|2009-04-30|Deka Products Limited Partnership|Air trap for a medical infusion device| US8425471B2|2007-02-27|2013-04-23|Deka Products Limited Partnership|Reagent supply for a hemodialysis system| US8393690B2|2007-02-27|2013-03-12|Deka Products Limited Partnership|Enclosure for a portable hemodialysis system| US8317492B2|2007-02-27|2012-11-27|Deka Products Limited Partnership|Pumping cassette| US10463774B2|2007-02-27|2019-11-05|Deka Products Limited Partnership|Control systems and methods for blood or fluid handling medical devices| US8543420B2|2007-09-19|2013-09-24|Fresenius Medical Care Holdings, Inc.|Patient-specific content delivery methods and systems| US9078971B2|2008-01-23|2015-07-14|Deka Products Limited Partnership|Medical treatment system and methods using a plurality of fluid lines| JP2011509803A|2008-01-23|2011-03-31|デカ・プロダクツ・リミテッド・パートナーシップ|Medical treatment system and method using multiple fluid lines| ITMI20080585A1|2008-04-04|2009-10-05|Gambro Lundia Ab|MEDICAL EQUIPMENT| US8057679B2|2008-07-09|2011-11-15|Baxter International Inc.|Dialysis system having trending and alert generation| US8771508B2|2008-08-27|2014-07-08|Deka Products Limited Partnership|Dialyzer cartridge mounting arrangement for a hemodialysis system| US8698741B1|2009-01-16|2014-04-15|Fresenius Medical Care Holdings, Inc.|Methods and apparatus for medical device cursor control and touchpad-based navigation| US8282829B2|2009-05-20|2012-10-09|Baxter International Inc.|System and method for automated data collection of twenty-four hour ultrafiltration and other patient parameters using wired or wireless technology| EP2445390B1|2009-06-22|2016-10-12|Analogic Corporation|Two-way authentication| US8685251B2|2009-12-05|2014-04-01|Home Dialysis Plus, Ltd.|Ultra-pasteurization for dialysis machines| US9020827B2|2009-10-16|2015-04-28|Baxter International Inc.|Peritoneal dialysis optimized using a patient hand-held scanning device| EP2493526B1|2009-10-30|2016-05-04|DEKA Products Limited Partnership|Apparatus and method for detecting disconnection of an intravascular access device| US8632485B2|2009-11-05|2014-01-21|Fresenius Medical Care Holdings, Inc.|Patient treatment and monitoring systems and methods| US10799117B2|2009-11-05|2020-10-13|Fresenius Medical Care Holdings, Inc.|Patient treatment and monitoring systems and methods with cause inferencing| WO2011069110A1|2009-12-05|2011-06-09|Home Dialysis Plus, Ltd.|Modular dialysis system| US8753515B2|2009-12-05|2014-06-17|Home Dialysis Plus, Ltd.|Dialysis system with ultrafiltration control| US8621213B2|2010-06-08|2013-12-31|Merge Healthcare, Inc.|Remote control of medical devices using instant messaging infrastructure| CA2804216C|2010-07-07|2019-01-15|Deka Products Limited Partnership|Medical treatment system and methods using a plurality of fluid lines| US9585810B2|2010-10-14|2017-03-07|Fresenius Medical Care Holdings, Inc.|Systems and methods for delivery of peritoneal dialysissolutions with integrated inter-chamber diffuser| WO2012162515A2|2011-05-24|2012-11-29|Deka Products Limited Partnership|Hemodial ysis system| AU2012259459B2|2011-05-24|2016-06-02|Deka Products Limited Partnership|Blood treatment systems and methods| US9999717B2|2011-05-24|2018-06-19|Deka Products Limited Partnership|Systems and methods for detecting vascular access disconnection| DE102011102872B4|2011-05-31|2018-11-22|Fresenius Medical Care Deutschland Gmbh|Blood treatment device| DE102011107795A1|2011-07-15|2013-01-17|Fresenius Medical Care Deutschland Gmbh|Method and device for remote monitoring and control of medical fluid management devices| ES2640953T3|2011-10-07|2017-11-07|Outset Medical, Inc.|Purification of heat exchange fluid for a dialysis system| WO2013067359A2|2011-11-04|2013-05-10|Deka Products Limited Partnership|Medical treatment system and methods using a plurality of fluid lines| US8769625B2|2011-11-17|2014-07-01|Fresenius Medical Care Holdings, Inc.|Remote control of dialysis machines| US10089443B2|2012-05-15|2018-10-02|Baxter International Inc.|Home medical device systems and methods for therapy prescription and tracking, servicing and inventory| JP6006542B2|2012-06-20|2016-10-12|日機装株式会社|Blood purification equipment| DE102012020945B4|2012-10-25|2019-10-10|Fresenius Medical Care Deutschland Gmbh|Apparatus, system and method for monitoring, displaying and operating medical fluid management devices| CN103830789A|2012-11-27|2014-06-04|深圳先进技术研究院|Hemodialysis system| US9579443B2|2013-01-10|2017-02-28|Fresenius Medical Care Holdings, Inc.|Peritoneal dialysis systems and related devices and methods| US10288881B2|2013-03-14|2019-05-14|Fresenius Medical Care Holdings, Inc.|Wearable interface for remote monitoring and control of a medical device| US20140267003A1|2013-03-14|2014-09-18|Fresenius Medical Care Holdings, Inc.|Wireless controller to navigate and activate screens on a medical device| CN105142692B|2013-03-14|2018-10-09|贝克斯特国际公司|The system and method exchanged for peritoneal dialysis with reusable supply unit| CN103623474A|2013-11-12|2014-03-12|禾研科技股份有限公司|Hematodialysis management system| JP6207019B2|2014-03-24|2017-10-04|日機装株式会社|Blood purification system| DE102014105916A1|2014-04-28|2015-10-29|B. Braun Avitum Ag|Data processing and communication device for recording patient data in therapy-free time| JP6657186B2|2014-04-29|2020-03-04|アウトセット・メディカル・インコーポレイテッドOutset Medical, Inc.|Dialysis system and method| US9800663B2|2015-03-06|2017-10-24|Fresenius Medical Care Holdings, Inc.|Associating dialysis accessories using near field communication| JP5964483B2|2015-06-10|2016-08-03|日機装株式会社|Blood purification system| DE102016111971A1|2016-06-30|2018-01-04|Fresenius Medical Care Deutschland Gmbh|Dedicated remote control of several dialysis machines| US20200027550A1|2018-07-17|2020-01-23|Icu Medical, Inc.|Maintaining clinical messaging during an internet outage|
法律状态:
2015-07-30| FGA| Letters patent sealed or granted (standard patent)|
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申请号 | 申请日 | 专利标题 SE0600931-0||2006-04-27|| SE0600931||2006-04-27|| US80344706P| true| 2006-05-30|2006-05-30|| US60/803,447||2006-05-30|| AU2007244000A|AU2007244000B2|2006-04-27|2007-04-26|Remote controlled medical apparatus| AU2013205933A|AU2013205933B2|2006-04-27|2013-05-20|Remote controlled medical apparatus|AU2013205933A| AU2013205933B2|2006-04-27|2013-05-20|Remote controlled medical apparatus| 相关专利
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